ea0041oc12.3 | Obesity | ECE2016
Rudovich Natalia
, Bernigau Wolfgang
, Pivovarova Olga
, Osterhoff Martin
, Sparwasser Andrea
, Bergmann Andreas
, Struck Joachim
, van Baak Marleen A
, Jebb Susan A
, Papadaki Angeliki
, Alfredo Martinez J
, Handjieva-Darlenska Teodora
, Kunesova Marie
, Hager Jorg
, Valsesia Armand
, Viguerie Nathalie
, Langin Dominique
, Astrup Arne
, Saris Wim H M
, Pfeiffer Andreas F H
Aims: Elevated levels of neurotensin (NT), a neurotransmitter and postprandial secreted intestinal hormone, are associated with an increased risk of diabetes, cardiovascular disease and breast cancer. Here we studied the regulation of circulating pro-NT (a stable NT precursor fragment) by weight loss and dietary interventions.Methods: DiOGenes is a pan-European controlled dietary intervention study in overweight adults who first lost body weight on an 8-...